Wednesday 1 August 2012

Treatment regimen of cholera

Antibiotic treatment of choice for treating cholera in an adult is a single dose of:
1 Tetracycline.
2 Co-trimoxazole.
3 Doxycycline.
4 Furazolidone.
Answer is 3        K. Park P.S.M. 17th ed./173.Table 9.124
Antibiotics used in the treatment of cholera
Antibiotics                                     Children                            Adults
Doxycycline once                             -                                    300 mg
Tetracycline                                 12.5 mg/kg                         500 mg
4 times a day for 3 days
Trimethroprim (TMP) TMP         5 mg/kg and                     TMP 160 mg
sulfamethoxazole (SMX) SMX     25 mg/kg                         SMX 800 mg
twice a day for 3 days

1) Erythromycin and chloramphenicol may also be used when none of the other recommended
antibiotics are available, or when Vibrio Cholerae 01 is resistant to the latter.
2) Doxycycline is the antibiotic of choice for adults (excepting pregnant women), since a single dose suffices.
3) TMP-SMX is the antibiotic of choice for children. Tetracycline is equally effective, but is not available everywhere in paediatric form.
4) Furazolidone is the antibiotic of choice for pregnant women.

6 comments:

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